منابع مشابه
Isolation of maxicircle component of kinetoplast DNA from hemoflagellate protozoa.
Maxicircle DNA has been isolated from the kinetoplast DNA of Leishmania tarentolae culture forms by bouyant separation in CsCl in the presence of the A + T-binding dye Hoechst 33258, after liberation from the kinetoplast DNA network by cleavage with the single-hit restriction endonuclease EcoRI. The purified linearized maxicircle DNA has a density in CsCl of 1.681 g/cm3 (79% A + T) and a molecu...
متن کاملMitochondrial Dna from Protozoa1
is known from the extensive genetic studies made in yeast (EPHRUSSI 1958) I;nd Neurospora (WAGNER and MITCHELL 1955) that certain defects associated with mitochondrial proteins are inherited under the control of a cytoplasmic element. However, the chemical nature and the specific location of such an element in the cytoplasm have not yet been elucidated. In recent years, evidence has been accumu...
متن کاملMitochondrial DNA Mutations, Pathogenicity and Inheritance
Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...
متن کاملAncient mitochondrial DNA from hair
The DNA content of hair [1,2] is typically low compared to other tissues, as hair cells undergo dehydration and catabolic breakdown of nucleic acids and organelles during keratinisation [3]. As a consequence, ancient hair specimens have not been widely used as a source of ancient DNA. However, mitochondrial DNA (mtDNA) has been extracted from degraded and old hair samples, including burnt speci...
متن کاملEliminating mitochondrial DNA from sperm.
Most eukaryotes show uniparental inheritance of mitochondrial DNA (mtDNA). In this issue of Developmental Cell, DeLuca and O'Farrell (2012) show that active elimination of mtDNA during sperm development in Drosophila ensures that mature spermatozoa are devoid of DNA.
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ژورنال
عنوان ژورنال: Genetics
سال: 1965
ISSN: 1943-2631
DOI: 10.1093/genetics/52.5.1051